Scientific platforms

At the edge of Synthetic Biology and Metabolic engineering to optimize various microorganisms such as :

• Bacteria, yeast, plant stem cells
• With a rare know-how in engineering microalgae, novel cell factories

For the sustainable production of vegan, safer and ethical bioinspired metabolites, bioactive peptides and proteins
for various industrial applications:

• Hyaluronic acid, a natural polysaccharide
• Bioactive peptides, polypeptides and proteins
  > Soluble (without insoluble aggregates)
  > Properly folded (endogenous formation of disulfide bonds essential for the stability and activity of numerous proteins)

Preserving the biodiversity and the environment while securing the supply chain (No use of scarce resources, no use of arable land, no seasonality, no use of hazardous
solvents nor expensive chemical reagents unlike conventional production processes).

Protéus is a pioneer in protein engineering technologies, boasting over 25 years of expertise in developing tailored enzymes and scaling-up biocatalytic processes.

We actively engage in partnership projects in which we can leverage our expertise to co-develop tailor-made solutions.

We also extend our capabilities to provide one-off services to meet specific needs.

Additionally, we offer a select range or proprietary products that showcase our expertise.

Explore our innovative solutions today!

OUR BIOPRODUCTS 

Proteus has developed its own range of proprietary products :

• More than 600 enzymes in collection, available on demand, covering 29 families of enzymes across main classes of enzymes (eg oxido-reductases, hydrolases, transferases, biomass treatment, cofactor recycling).

• Download enzyme collection list
• Order a screening kit (link to formulaire with following address: seqenzym@seqens.com

OUR ACHIEVMENTS

• For more than 20 years, Proteus by Seqens has been developing tailor made enzymes and biocatalytic processes for its customers in various industries
• We have developed an offer adapted to each application, depending on its specific needs and regulatory constraints

Examples of published projects

• Synthesis of a cosmetic ingredient using a biocatalyst catalyzing the transesterification reaction. Three parameters had to be improved: selectivity towards the targeted alcohol group (3 possibilities), selectivity towards an impurity which is present in the substrate and very similar to the substrate ester and rate of conversion.
  Using EvosightTM, enzymes improved for each parameter were obtained.

• Selectivity towards the targeted alcohol group: 95% vs 85%
• Selectivity towards the impurity: 1% vs 3%
• Rate of conversion: gain of 20%

A 34,000-square-metre science platform.

Seqens’Lab offers a unique ecosystem, dedicated to our customers to accelerate their projects from discovery to production and sales. Pharmaceuticals, personal care and specialty ingredients are the key markets served by Seqens.

Close to Paris, Seqens’Lab is the centre of excellence for developing a totally unique package of R&D services.

As an R&D center that meets the highest standards, Seqens’Lab brings together the group’s key skills and expertise through

• Medical synthesis laboratory
• Chemical process development laboratory
• Crystallization process development laboratory
• GMP Kilo-Lab
• Solid state analysis laboratory including polymorph screening
• Analytical development laboratory
• Expertise in Process Safety
• Kinetic and thermodynamic simulation tools
• Batch production capacities for pre-clinical and clinical studies
• Quality Control laboratory for clinical batch release and stability studies

All this in a GMP quality environment.