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Plateforms

Comprehensive global R&D platform with unique scientific skills​

Alganelle by SEQENS

Unlocking the power of Nature.

Disruptive technologies in synthetic biology​.

Alganelle is an innovative biotechnology company at the cutting edge of Synthetic Biology and
Metabolic engineering applied to various microorganisms, including microalgae, used as cell
factories for the sustainable production of vegan, safer and ethical bioinspired metabolites, bioactive peptides and proteins for various industrial applications.

Based on 30 years of experience and its disruptive technologies, Alganelle offers to its clients with active ingredients of very high quality, safer and obtained from environmentally sustainable processes preserving the biodiversity and the environment while securing the supply chain.

>> Know more about Alganelle by SEQENS

Sy
Synthetic Biology
  • Genetic and metabolic engineering
Ce
Cell Factories
  • In vivo biocatalysis
Pr
Production of High Value molecules vegan, sustainable, safer and ethical
  • Bioactive peptides/proteins
  • Metabolites (polysaccharides, oligosaccharides carotenoids…)
  • Biomaterials
  • Microorganism optimization
Al
Alganelle Proprietary Products
  • 3 patents filed for technology
  • Vegan peptides/proteins of Collagen-like and Elastin-like
Hy
Hyaluronic Acid
  • Metabolic engineering
Ac
4 Active Pharmaceutical Ingredients (API)

Innovative Biotech company with 30 years of experience and 4 patents

At the edge of Synthetic Biology and Metabolic engineering to optimize various microorganisms such as :

  • Bacteria, yeast, plant stem cells
  • With a rare know-how in engineering microalgae, novel cell factories

 

For the sustainable production of vegan, safer and ethical bioinspired metabolites, bioactive peptides and proteins for various industrial applications:

  • Hyaluronic acid, a natural polysaccharide
  • Bioactive peptides, polypeptides and proteins
    > Soluble (without insoluble aggregates)
    > Properly folded (endogenous formation of disulfide bonds essential for the stability and activity of numerous proteins)

Preserving the biodiversity and the environment while securing the supply chain (No use of scarce resources, no use of arable land, no seasonality, no use of hazardous
solvents nor expensive chemical reagents unlike conventional production processes).

>> Click here to discover Alganelle by SEQENS website

Protéus by SEQENS

 

ENZYMES DEVELOPMENT AND INDUSTRIAL BIOCATALYSIS

  • Co-development Partnerships 
  • One-off Services 
  • Proprietary Products
Download our SEQUENZYM brochure

COMPLEMENTARY BIOTECHNOLOGY PLATFORMS

Protéus is a pioneer in protein engineering technologies, boasting over 25 years of expertise in developing tailored enzymes and scaling-up biocatalytic processes.

We actively engage in partnership projects in which we can leverage our expertise to co-develop tailor-made solutions.

We also extend our capabilities to provide one-off services to meet specific needs.

Additionally, we offer a select range or proprietary products that showcase our expertise.

Explore our innovative solutions today!

History

Created in 1998 ​and within SEQENS since 2017​

  • Multidisciplinary team of 20 Research ​scientists & experts

Offer

Pharma Flavor & Fragrances Cosmetics Food & Feed Agrosciences Chemistry & Detergency

  • Biocatalysis services​
  • Enzyme screening​
  • Biocatalyst development & optimization​
  • Biocatalysis scale-up​
  • Multi-tons manufacturing​

Collection

4800 microorganism (Bacteria, Archaea, Fungi, microalgae…) including over 1500 sequenced (meta)genomes [unique pool of millions of enzymes]

  • Collection of more than 600 enzymes (all classes covered)

Technology

Patented directed evolution technologies (EvoSightTM & L-ShufflingTM)

  • In silico design of smart libraries & molecular dynamic analysis

Industry

Automated high-throughput screening platform

  • Fermentation scale-up from Lab to 300L bioreactors

Proteus by Seqens offers a powerful platform to access unique enzymes from biodiversity and state-of-the-art proprietary technologies for molecular engineering.

Its expertise includes biocatalytic processes development and, through Seqens group, scale-up and industrial production capabilities.

BICROBIOLOGY – SCREENING OF BIODIVERSITY

  • Identify from Nature’s diversity the best performing native enzymes

PROTEIN ENGINEERING – TAILOR MADE ENZYMES

  • Powerful tools for improving enzyme efficiency for target applications

BIOCATALYTIC PROCESS DEVELOPMENT

  • Highly selective biocatalytic steps for increased competitiveness
Learn more about Biocatalysis and our methodology

Our Bioproducts

Proteus has developed its own range of proprietary products:

  • More than 600 enzymes in collection, available on demand, covering 29 families of enzymes across main classes of enzymes (eg oxido-reductases, hydrolases, transferases, biomass treatment, cofactor recycling).
  • Download enzyme collection list
  • Order a screening kit (link to formulaire with following address: seqenzym@seqens.com)

BIOTCATALYST FOR SUCROSE CONVERSION INTO FRUCTO-OLIGOSACCHARIDES

  • Fructo-oligosaccharides (FOS) are a natural sweet-tasting, low-calorie sugar alternative.

BIOCATALYST FOR ESTOLIDES PRODUCTION

  • Innovative fatty acid polyesters thanks to high performing lipases

BIOMASS HYDROLYSIS COCKTAIL

  • A range of cellulases at the highest level for cellulose hydrolysis

Our Achievments

  • For more than 20 years, Proteus by Seqens has been developing tailor made enzymes and biocatalytic processes for its customers in various industries
  • We have developed an offer adapted to each application, depending on its specific needs and regulatory constraints

Examples of published projects

  • Synthesis of a cosmetic ingredient using a biocatalyst catalyzing the transesterification reaction. Three parameters had to be improved: selectivity towards the targeted alcohol group (3 possibilities), selectivity towards an impurity which is present in the substrate and very similar to the substrate ester and rate of conversion.
    Using EvosightTM, enzymes improved for each parameter were obtained.
  • Selectivity towards the targeted alcohol group: 95% vs 85%
  • Selectivity towards the impurity: 1% vs 3%
  • Rate of conversion: gain of 20%

 

SEQENS’Lab

 

A DEVELOPMENT ACCELERATOR

A 34,000-square-metre science platform.

Seqens’Lab offers a unique ecosystem, dedicated to our customers to accelerate their projects from discovery to production and sales. Pharmaceuticals, personal care and specialty ingredients are the key markets served by Seqens.

Close to Paris, Seqens’Lab is the centre of excellence for developing a totally unique package of R&D services.

THE CENTRE OF EXCELLENCE FOR DEVELOPING A TOTALY UNIQUE PACKAGE OF R&D SERVICES.

As an R&D center that meets the highest standards, Seqens’Lab brings together the group’s key skills and expertise through

  • Medical synthesis laboratory
  • Chemical process development laboratory
  • Crystallization process development laboratory
  • GMP Kilo-Lab
  • Solid state analysis laboratory including polymorph screening
  • Analytical development laboratory
  • Expertise in Process Safety
  • Kinetic and thermodynamic simulation tools
  • Batch production capacities for pre-clinical and clinical studies
  • Quality Control laboratory for clinical batch release and stability studies

All this in a GMP quality environment.

Learn more about Seqens’Lab capacity
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1.

R&D Building ​

  • Chemistry, Analytics, Kilo-Lab​
2.

1st Biotech​ ​

  • GenEvolutioN​
  • In-vitro testing services​
3.

Building 1​​

  • 1000m² of laboratories​
  • 800 m² of Offices​
  • 200 m² of meeting rooms​
  • 4000 m² of classified rooms​
  • 600 m² of GXP archiving storage​
  • 1500 m² of storage​
4.

Building 2

  • 2000 m3 of GXP Storage
5.

Building 3

  • 600 m² of Offices​
  • 150 m² of meeting rooms​
6.

Warehouse​

7.

Pilot plant​