Scientific platforms
Comprehensive global R&D platform with unique scientific skills
Alganelle by SEQENS
Unlocking the power of Nature.
Disruptive technologies in synthetic biology.
Alganelle is an innovative biotechnology company at the cutting edge of Synthetic Biology and
Metabolic engineering applied to various microorganisms, including microalgae, used as cell
factories for the sustainable production of vegan, safer and ethical bioinspired metabolites, bioactive peptides and proteins for various industrial applications.
Based on 30 years of experience and its disruptive technologies, Alganelle offers to its clients with active ingredients of very high quality, safer and obtained from environmentally sustainable processes preserving the biodiversity and the environment while securing the supply chain.
- Genetic and metabolic engineering
- In vivo biocatalysis
- Bioactive peptides/proteins
- Metabolites (polysaccharides, oligosaccharides carotenoids…)
- Biomaterials
- Microorganism optimization
- 3 patents filed for technology
- Vegan peptides/proteins of Collagen-like and Elastin-like
- Metabolic engineering
Innovative Biotech company with 30 years of experience and 4 patents
At the edge of Synthetic Biology and Metabolic engineering to optimize various microorganisms such as :
- Bacteria, yeast, plant stem cells
- With a rare know-how in engineering microalgae, novel cell factories
For the sustainable production of vegan, safer and ethical bioinspired metabolites, bioactive peptides and proteins for various industrial applications:
- Hyaluronic acid, a natural polysaccharide
- Bioactive peptides, polypeptides and proteins
> Soluble (without insoluble aggregates)
> Properly folded (endogenous formation of disulfide bonds essential for the stability and activity of numerous proteins)
Preserving the biodiversity and the environment while securing the supply chain (No use of scarce resources, no use of arable land, no seasonality, no use of hazardous
solvents nor expensive chemical reagents unlike conventional production processes).
COMPLEMENTARY BIOTECHNOLOGY PLATFORMS
Protéus is a pioneer in protein engineering technologies, boasting over 25 years of expertise in developing tailored enzymes and scaling-up biocatalytic processes.
We actively engage in partnership projects in which we can leverage our expertise to co-develop tailor-made solutions.
We also extend our capabilities to provide one-off services to meet specific needs.
Additionally, we offer a select range or proprietary products that showcase our expertise.
Explore our innovative solutions today!
History
Created in 1998 and within SEQENS since 2017
- Multidisciplinary team of 20 Research scientists & experts
Offer
Pharma Flavor & Fragrances Cosmetics Food & Feed Agrosciences Chemistry & Detergency
- Biocatalysis services
- Enzyme screening
- Biocatalyst development & optimization
- Biocatalysis scale-up
- Multi-tons manufacturing
Collection
4800 microorganism (Bacteria, Archaea, Fungi, microalgae…) including over 1500 sequenced (meta)genomes [unique pool of millions of enzymes]
- Collection of more than 600 enzymes (all classes covered)
Technology
Patented directed evolution technologies (EvoSightTM & L-ShufflingTM)
- In silico design of smart libraries & molecular dynamic analysis
Industry
Automated high-throughput screening platform
- Fermentation scale-up from Lab to 300L bioreactors
Proteus by Seqens offers a powerful platform to access unique enzymes from biodiversity and state-of-the-art proprietary technologies for molecular engineering.
Its expertise includes biocatalytic processes development and, through Seqens group, scale-up and industrial production capabilities.
BICROBIOLOGY – SCREENING OF BIODIVERSITY
- Identify from Nature’s diversity the best performing native enzymes
PROTEIN ENGINEERING – TAILOR MADE ENZYMES
- Powerful tools for improving enzyme efficiency for target applications
BIOCATALYTIC PROCESS DEVELOPMENT
- Highly selective biocatalytic steps for increased competitiveness
Our Bioproducts
Proteus has developed its own range of proprietary products:
- More than 600 enzymes in collection, available on demand, covering 29 families of enzymes across main classes of enzymes (eg oxido-reductases, hydrolases, transferases, biomass treatment, cofactor recycling).
- Download enzyme collection list
- Order a screening kit (link to formulaire with following address: seqenzym@seqens.com)
BIOTCATALYST FOR SUCROSE CONVERSION INTO FRUCTO-OLIGOSACCHARIDES
- Fructo-oligosaccharides (FOS) are a natural sweet-tasting, low-calorie sugar alternative.
BIOCATALYST FOR ESTOLIDES PRODUCTION
- Innovative fatty acid polyesters thanks to high performing lipases
BIOMASS HYDROLYSIS COCKTAIL
- A range of cellulases at the highest level for cellulose hydrolysis
Our Achievments
- For more than 20 years, Proteus by Seqens has been developing tailor made enzymes and biocatalytic processes for its customers in various industries
- We have developed an offer adapted to each application, depending on its specific needs and regulatory constraints
Examples of published projects
- Synthesis of a cosmetic ingredient using a biocatalyst catalyzing the transesterification reaction. Three parameters had to be improved: selectivity towards the targeted alcohol group (3 possibilities), selectivity towards an impurity which is present in the substrate and very similar to the substrate ester and rate of conversion.
Using EvosightTM, enzymes improved for each parameter were obtained.
- Selectivity towards the targeted alcohol group: 95% vs 85%
- Selectivity towards the impurity: 1% vs 3%
- Rate of conversion: gain of 20%
- For general informations contact: infoproteus@seqens.com
- For custom-made enzyme kits: seqenzym@seqens.com
SEQENS’Lab
A DEVELOPMENT ACCELERATOR
A 34,000-square-metre science platform.
Seqens’Lab offers a unique ecosystem, dedicated to our customers to accelerate their projects from discovery to production and sales. Pharmaceuticals, personal care and specialty ingredients are the key markets served by Seqens.
Close to Paris, Seqens’Lab is the centre of excellence for developing a totally unique package of R&D services.
THE CENTRE OF EXCELLENCE FOR DEVELOPING A TOTALY UNIQUE PACKAGE OF R&D SERVICES.
As an R&D center that meets the highest standards, Seqens’Lab brings together the group’s key skills and expertise through
- Medical synthesis laboratory
- Chemical process development laboratory
- Crystallization process development laboratory
- GMP Kilo-Lab
- Solid state analysis laboratory including polymorph screening
- Analytical development laboratory
- Expertise in Process Safety
- Kinetic and thermodynamic simulation tools
- Batch production capacities for pre-clinical and clinical studies
- Quality Control laboratory for clinical batch release and stability studies
All this in a GMP quality environment.
R&D Building
- Chemistry, Analytics, Kilo-Lab
1st Biotech
- GenEvolutioN
- In-vitro testing services
Building 1
- 1000m² of laboratories
- 800 m² of Offices
- 200 m² of meeting rooms
- 4000 m² of classified rooms
- 600 m² of GXP archiving storage
- 1500 m² of storage
Building 2
- 2000 m3 of GXP Storage
Building 3
- 600 m² of Offices
- 150 m² of meeting rooms